![]() ![]() The most common adverse reactions (side effects) with Andexxa were: In another study with 234 patients who experienced a major bleed while taking Xarelto or Eliquis, Andexxa, reversed blood thinning by 93%.The median decrease in anti-Factor Xa activity from baseline was 97% for rivaroxaban (Xarelto) and 92% for apixaban (Eliquis).In a Phase 3 studies in healthy volunteers, Andexxa rapidly and significantly reversed anti-Factor Xa activity within 2 minutes after a bolus injection and sustained these reductions throughout the 2-hour continuous infusion. ![]() Andexxa is also approved to reduce the anticoagulant effect of Factor Xa inhibitor Eliquis (apixaban). It neutralizes the anticoagulant effect of Xarelto (rivaroxaban). ![]() How does Andexxa work to stop bleeding?Īndexxa works by acting as a trap for oral and injectable Factor Xa inhibitors, binding to the drug to reverse the anticoagulant effect. Vitamin K is often used to reverse bleeding from warfarin but doesn't work for drugs like Xarelto.
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